Female factors that affect fertility include the following categories: Infertility is a problem that involves both partners.
Diagnostic testing is unnecessary if the couple has not attempted to conceive for at least 1 year, unless the woman is age 35 years or older, or if they have a history of a male factor infertility, endometriosis, a tubal factor, diethylstilbestrol (DES) exposure, pelvic inflammatory disease, or pelvic surgery.
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However, data show that 6-10% of women who are fertile demonstrate an inadequate luteal phase, which confirms the need for a better understanding of normal variations in the menstrual cycle and in variations that could be pathologic.
Endometrial dating was performed according to Noyes’ criteria.
Biopsies from 11 patients were analyzed for gene expression with the Affymetrix HG U133 Plus 2 microarray.
Attention to qualitative changes in 8 morphological factors is most useful in dating the endometrial biopsy.
During the 1st week of luteal activity, attention should be focused on changes occurring in gland epithelium: gland mitosis, pseudostratification of nuclei, basal vacuolation, and secretion.
Management of any underlying female and/or male factors affecting fertility may include medical treatment (eg, pharmacotherapy), surgical intervention, or both.